How do you approach recurrent grade 3 anaplastic astrocytoma after gross total resection followed by RT/adjuvant temozolomide?   

Guidelines do not provide strong guidance on who will benefit from temozolomide vs PCV or when to consider re-challenging with temozolomide.



Answer from: Medical Oncologist at Academic Institution
Comments
Radiation Oncologist at University of Alabama at Birmingham
Agree with all of above, and would just add that r...
Medical Oncologist at Cancer Care Specialists/ Renown Oncology / UNR
If it is gr4, would you do CCNU + Avastin outside ...
Medical Oncologist at University of Utah Huntsman Cancer Institute
I agree that be useful particularly for trial elig...
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