Is it acceptable to treat newly diagnosed small cell lung cancer with limited brain metastasis with SRS upfront in order to minimize delays to systemic therapy?   

This has become standard practice at our institution for patients with a good performance status, with whole brain radiotherapy given after the completion of concurrent chemoradiation to the chest (or not at all, if the patient is elderly or refuses it). On the one hand, it's a pragmatic approach to avoid delaying chemotherapy, but on the other hand, we know whole brain RT improves survival in limited and extensive stage disease (and maybe for the patients with brain metastasis who were included in these studies but not thought to have brain mets because of the imaging done at the time). 



Answer from: Radiation Oncologist at Academic Institution
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Radiation Oncologist at CHI St. Vincent Cancer Treatment Center
We will also delay whole brain radiation in newly ...
Radiation Oncologist at Oakland University William Beaumont School of Medicine
Until you stop the chemotherapy and they all come ...
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Answer from: Radiation Oncologist at Community Practice
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Radiation Oncologist at Thomas Jefferson University Hospital
Well said, @Andrew T. Turrisi. I subscribe to all ...
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Answer from: Radiation Oncologist at Community Practice

Answer from: Radiation Oncologist at Community Practice
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Radiation Oncologist at University of Alabama at Birmingham
This is a great trial! Can't wait to see the resul...
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Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice

Answer from: Radiation Oncologist at Academic Institution

Answer from: Radiation Oncologist at Community Practice

Answer from: Radiation Oncologist at Academic Institution