Would you recommend adjuvant chemoradiation after adjuvant chemotherapy for a patient with pancreatic adenocarcinoma s/p a whipple resection with negative margins?

Topics: Radiation Oncology • Gastrointestinal Cancers

What pathologic factors would you use to make your recommendation?

Answer from: Radiation Oncologist at Academic Institution

There are three options here in my practice. 1) Treat, 2) don't treat, and 3) "watch and wait, then ablate" (for a local recurrence). In general, I treat patients with CXRT who have positive margins (IMRT 45 Gy/25# to regional volume with SIB of 62.5 Gy to the margin. If it is an R2 resection (whic...

Comments

Radiation Oncologist at PEACHTREE RADIATION ONCOLOGY SERVICES, P.C.
Have you published your data on treating patients ...

Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
Not yet, we will submit it to ASTRO this year.

Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
*those cases were from MSK, all treated in the las...

Radiation Oncologist at KUMC
Would a patient with negative margins post-whipple...

Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
I would watch and wait. There is no clear OS benef...

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