Hematology

Anifrolumab

Questions discussed in this category

Would you consider anifrolumab in the management of hematologic manifestations in SLE?

2 Answers available

Papers discussed in this category

N Engl J Med, 2019 Dec 18

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

Ann Rheum Dis, 2022 Mar 25

Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III trials.

Lupus science & medicine, 2018

Type I interferon receptor blockade with anifrolumab corrects innate and adaptive immune perturbations of SLE.

Arthritis Rheum,

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease.

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