Hospital Medicine

General Hepatology

Questions discussed in this category

How do you evaluate and manage acute alcohol withdrawal when symptom-driven protocols are confounded/unreliable?

For instance, what do you do when patients have chronic tremors, cognitive impairment, hypertension, etc.?

3 Answers available

How do you use IVC caliber and collapsibility to guide decisions about diuresis?

4 Answers available

How do you consider sending fungal studies in a patient with pneumonia?

Considering the recent article in CHEST that describes the increasing incidence of fungal pneumonia Azar. Chest 2024

3 Answers available

Do you recommend restarting GLP-1RA after bariatric surgery if they tolerated it before the surgery?

2 Answers available

How do you determine whether to limit volume removal during therapeutic paracentesis in a patient without acute or chronic kidney disease?

3 Answers available

What precautions should be taken when discharging a patient from the medical setting on new medication assisted therapy for alcohol use disorder?

This is based on the recent publication by Bernstein et al., PMID 38551564 which investigated the increased rate of initiation of MAUD in the hospital...

5 Answers available

What additional workup would you recommend for a patient with a liver abscess caused by Fusobacterium and Aggregatibacter, who has had unrevealing endoscopies and no other abdominal masses on a CT scan?

1 Answer available

Which patients with cirrhosis and portal hypertension are ideal candidates to undergo TIPS to reduce perioperative risk in anticipation of an elective surgery?

1 Answer available

Can defibrotide be given safely for VOD in patients with refractory thrombocytopenia to platelet transfusions?

1 Answer available

Do you avoid terlipressin for patients with hepatorenal syndrome who have a serum sodium level less than 125 mEq/L?

2 Answers available

Papers discussed in this category

Blood, 2016-03-31

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure.

Bone marrow transplantation, 2016-07

Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation.

Bone marrow transplantation, 2018-02

Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in pediatric patients: a new classification from the European society for blood and marrow transplantation.

British journal of haematology, 2020 Mar 04

Modified diagnostic criteria, grading classification and newly elucidated pathophysiology of hepatic SOS/VOD after haematopoietic cell transplantation.

Blood advances, 2022 Jan 11

Defibrotide: real-world management of veno-occlusive disease/sinusoidal obstructive syndrome after stem cell transplant.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2020 Jan-Dec

A Meta-Analysis Evaluating the Incidence of Bleeding Events With Intravenous Defibrotide Treatment Outside the Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Setting.

Bone marrow transplantation, 2022 Dec 23

Real-world use of defibrotide for veno-occlusive disease/sinusoidal obstruction syndrome: the DEFIFrance Registry Study.

The New England journal of medicine, 2021 Mar 04

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome.

Scientific reports, 2023 Nov 28

Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity.

JCI insight, 2023 Jun 22

The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission.

Hepatology (Baltimore, Md.), 2012 Apr

Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials.

Am J Respir Crit Care Med, 2019 Sep 1