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Nephrology

Scleroderma Renal Crisis   

Questions discussed in this category


What are some important considerations for use of ACE inhibition in scleroderma renal crisis patients who require dialysis?
For example, is captopril dialyzable? 
1 Answer available

What is the approach to use of ACE inhibitors for suspected scleroderma renal crisis in patients with only mildly elevated BP and renal artery stenosis?
2 Answers available

How do you manage patients with systemic sclerosis and chronic thrombotic microangiopathy on renal biopsy, but no other evidence of scleroderma renal crisis?
Patient with nephrotic range proteinuria, but there is no evidence of active TMA on renal biopsy.
1 Answer available

When is a kidney biopsy warranted in a patient with possible scleroderma renal crisis?
1 Answer available

How do you approach the use of endothelin receptor antagonists in patients with scleroderma renal crisis and hypertension refractory to maximum ACE inhibition and calcium channel blockers?
1 Answer available
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Papers discussed in this category


QJM, 2013 May 21
Targeting the endothelin axis in scleroderma renal crisis: rationale and feasibility.

Annals of clinical and laboratory science, 2008
Nephrotic range proteinuria: rare manifestation of scleroderma renal crisis.

International journal of general medicine, 2019 Sep 02
Renal pathology and clinical associations in systemic sclerosis: a historical cohort study.

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  • Medical Oncology
  • Endocrine Tumors
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