Nephrology

Pediatric Hematology

Questions discussed in this category

How would you approach post-operative VTE prophylaxis for renal transplant in patients with a prior history of provoked VTE?

Are there specific guidelines for managing this patient population?

1 Answer available

For patients with suspected complement-mediated TMA, are there specific clinical or laboratory parameters that can help guide the decision for starting empirical treatment (e.g., eculizumab) while awaiting the results of complement testing?

1 Answer available

How do you dose apixaban in patients with CrCl <30 mL/minute?

1 Answer available

Do you consider starting hydroxyurea in a patient with hemoglobin S-beta thalassemia with chronic kidney disease secondary to FSGS?

No transfusion dependence but has hemoglobin in the 8-9 g/dl range.

1 Answer available

Do you hold IV iron in the setting of active infection?

1 Answer available

Is there any role for iron chelation in a patient with iatrogenic transfusion-induced iron overload such as in patients with end-stage kidney or liver disease?

Does transplant eligibility make a difference for management?

1 Answer available

In which patients with atypical HUS would you consider eculizumab discontinuation?

Given the high cost of eculizumab, are there patient characteristics that inform which patients, if any, should be on indefinite therapy versus a time...

2 Answers available

Papers discussed in this category

Blood, 2017-07-20

Eculizumab cessation in atypical hemolytic uremic syndrome.

Clin J Am Soc Nephrol, 2016 Oct 31

Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation.

Blood, 2020 Dec 03

Eculizumab discontinuation in children and adults with atypical haemolytic uremic syndrome: a prospective multicentric study.

Circulation, 2022 Nov 06

A Randomized Controlled Trial Comparing Apixaban With the Vitamin K Antagonist Phenprocoumon in Patients on Chronic Hemodialysis: The AXADIA-AFNET 8 Study.

Circulation, 2022 Nov 06

Apixaban for Patients With Atrial Fibrillation on Hemodialysis: A Multicenter Randomized Controlled Trial.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2021 Dec 06

Antithrombotic Management in Adult Kidney Transplantation: A European Survey Study.

Nephrology

Pediatric Hematology

Questions discussed in this category

Papers discussed in this category

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