Do you hold CRRT for a period of time before performing a diuretic challenge in a patient with whom you are assessing for the ability to wean off of continuous dialysis?

You may want to sit down for this answer, I think the diuretic challenge is overrated and if I’m not mistaken, it was really developed to see if a patient may need to start RRT for Aki, not come off it.

I would hardly use it on a patient with aki on Crrt for a decision. It isn’t rocket science to determine aki recovery, patient urine output spontaneously increases and I cut back clearance rate and follow numbers and volume status. And increasing urine after lasix is not increased gfr as it is if...

Please check this reference by Uchino et al., PMID 19623048. Urine output is a major determinant of the success of CRRT weaning. Using a diuretic challenge as a "stress" test of the kidney function (Rewa et al., PMID 31035185) might not be a bad idea as you are contemplating weaning off CCRT (evidence-free zone!). However, you have to avoid hypotension as it is critical time to maintain good perfusion of the kidneys while likely recovering. If the urine output response was brisk, drop the ultraf...