Do you stop tolvaptan below a certain eGFR in a patient with autosomal dominant polycystic kidney disease?
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Do you continue tolvaptan in patients with ADPKD and CKD Stage 5 who have not required renal replacement therapy?
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1 Answer
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Nephrology · UCSF
Answered on
In general, the practical guidelines support continuing tolvaptan until dialysis or transplant (Chebib and Torres, PMID 33705818). There are situations where I will discontinue sooner, either due to apparent lack of benefit, due to precipitous, unexpectedly rapid decline or accelerated decline, or, ...
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