Mednet Logo

How do you manage a patient with a nonspecific platelet function disorder and heterozygous protein C deficiency during pregnancy?

Specifically - patient who had mild aggregation defect with ADP which corrected in third trimester of pregnancy. Would it be appropriate or necessary to give DDAVP prior to neuraxial anesthesia?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Hematology · University of Wisconsin
Answered on

Assuming platelet function testing was done as part of a more comprehensive assessment of hemostasis and that there are no other detectable hemostatic defects (e.g., low von Willebrand factor level prior to 3rd trimester), I would not recommend giving DDAVP unless the patient has a significant bleed...

Join for free or sign in to see the full answer