In a young female with severe osteoporosis due to congenital estrogen deficiency, can estrogen be prescribed if genetic testing for congenital disorders reveals a heterozygous Factor V Leiden mutation?   

No prior thrombosis; no family history of thrombosis. As per endocrine, the only useful therapy for the osteoporosis is estrogen. 

Answer from: at Academic Institution
Medical Oncologist at NYU Langone Medical Center
I completely agree with your comments. The genetic...
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