2025 ESC Guidelines for the management of cardiovascular disease and pregnancy.

European heart journal 2025 Nov 14

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Could plasmapheresis be reasonably considered in pregnant patients for primary prevention in asymptomatic familial hypercholesterolemia, and if so, is there an LDL cutoff that would prompt consideration to proceed?

New answer by at University of Southern California (December 24, 2025)

Plasmapheresis/LDL apheresis is considered a safe and effective option for maternal LDL-C lowering in pregnancy, especially in women with homozygous FH, where it is considered...

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