2007 Jul 06

A review of the management by hysterectomy of 25 cases of gestational trophoblastic tumours from March 1993 to January 2006.

Abstract

We reviewed 25 cases of gestational trophoblastic tumours referred for surgical management from Charing Cross Hospital (the London centre for gestational trophoblastic disease [GTD]) over a 13-year period. The operation performed was total abdominal hysterectomy, with lymph node sampling in 9/25 (36%) women and bilateral salpingo-oophorectomy in 11/25 (44%) women. Radical hysterectomy and unilateral parametrectomy was required in 3/25 (12%) women. Three of 25 (12%) women failed to survive, i.e. the overall rate of survival was 88%. Management by hysterectomy of primary drug-resistant and relapse cases of GTD is a useful and safe adjunct to chemotherapy.

Related Questions

Would you offer adjuvant therapy for a patient with stage I high risk invasive mole after hysterectomy?

1 Answers

Mednet Member

Gynecologic Oncology · Center of Hope

Great question! For this patient’s unique situation, although adjuvant chemotherapy is entirely appropriate, I believe it may not be necessary. The decision to offer adjuvant therapy may be cautiously delayed pending her immediate post-hysterectomy hCG levels. If there is a rapid decline in hCG, obs...