Oncologist 2023 Feb 8
Clinical Implications and Treatment Strategies for ESR1 Fusions in Hormone Receptor-Positive Metastatic Breast Cancer: A Case Series.
Related Questions
New answer by Medical Oncologist at H Lee Moffitt Cancer Center, University of South Florida (March 28, 2024)
These ESR1 fusions usually replace the ligand binding domain (LBD) of the estrogen receptor alpha protein with a portion of another protein like AKAP12. The fusion protein can...
New answer by Medical Oncologist at Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty (April 27, 2025)
In a patient with BRCA2 mutation and contralateral axillary recurrence of ER+ IDC with an ESR1 CCDC170 fusion on NGS testing, would you use standard adjuvant AI therapy or con...