Combined nivolumab and ipilimumab with or without stereotactic body radiation therapy for advanced Merkel cell carcinoma: a randomised, open label, phase 2 trial.

Lancet 2022 Sep 24

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Would you consider adjuvant immunotherapy for a patient with high-risk (N3 nodes) Merkel cell carcinoma following definitive surgical resection and adjuvant radiation therapy?

New comment by Radiation Oncologist at West Virginia University ( May 30, 2025)

I would debate your use of radiotherapy as an "unproven modality" in managing MCC. The fact that there is no level 1 data proving its benefit doesn't mean that there isn't one...

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