Lung cancer (Amsterdam, Netherlands) 2025 Aug 26
Early pseudo-progression of brain metastases following tarlatamab therapy in relapsed small cell lung cancer.
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New answer by Medical Oncologist at The University of Texas MD Anderson Cancer Center (February 5, 2026)
I would absolutely continue tarlatamab in this scenario. While there is evidence of at least some activity of tarlatamab in the CNS (e.g., Zhang et al., PMID 40126456), the ef...