Equivalent Efficacy and Decreased Rate of Overcorrection in Patients With Syndrome of Inappropriate Secretion of Antidiuretic Hormone Given Very Low-Dose Tolvaptan.

Kidney Med 2020 Jan-Feb

Related Questions

Would you recommend starting tolvaptan at 7.5 mg per day, which is half the typical starting dose, to reduce the risk of overcorrection in an inpatient with SIADH and a serum sodium level of 122 mEq/L?

New answer by at Southern Utah Kidney And Hypertension Center (February 1, 2026)

Yes. It’s safe to use that way at 7.5 mg, and overcorrection is very rare. Dr. @Rodby’s paper is very nice in explaining that.

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