Journal of clinical psychopharmacology 1990-02
Is buspirone effective for panic disorder?
ABSTRACT
Buspirone was compared with imipramine and placebo in the treatment of panic disorder in an 8-week, double-blind controlled study of 52 randomly assigned patients. The side effect profile of buspirone was less disruptive than that of imipramine. Buspirone was not significantly superior to placebo in its antipanic or anxiolytic effects in panic disorder patients.
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New comment by at TAC Telepsychiatry ( April 5, 2025)
What I've found is that if I start the Buspirone at 5 mg, it does nothing. Then the patient's anxiety about it not working makes it not work, even as you go to a higher dose. ...