Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2024 Oct 29
Multisociety clinical practice guidance for the safe use of glucagon-like peptide-1 receptor agonists in the perioperative period.
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How many days prior to elective major surgery do you recommend holding oral GLP 1 R agonist therapy?
New answer by at Medstar Health (October 1, 2025)
Oral semaglutide is dosed daily due to challenges with absorption, but once absorbed has about a 7-day half-life. Therefore, the risks due to slowing gastric emptying and pote...