International journal of radiation oncology, biology, physics 2010-03-01
Radiation dose-volume effects in the lung.
ABSTRACT
The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.
Related Questions
Do you define it as whole lungs (inc. tumor) or whole lungs minus GTV, CTV, ITV, or PTV?
New answer by Radiation Oncologist at Varian Medical Systems/Allegheny health network (November 8, 2014)
Most of the published data is on both lungs minus PTV. QUANTEC accounts for all normal lung treated minus GTV, and this is what we favor now. There is a small difference in nu...