Topics:
Neurology • Neuro-Ophthalmology
What is the utility and yield of CSF studies for orbital apex syndrome?
Although probably more familiar to ophthalmologists, orbital apex syndrome refers to the consequence of any kind of swelling or mass effect within the posterior orbit. Commonly this is the result of thyroid orbitopathy, but rarely there are infectious, traumatic and neoplastic causes. Once appropriate neuroimaging is obtained, how useful is CSF analysis in this scenario?
Answer from: at Academic Institution
"Orbital apex syndrome" is a description of WHERE the problem is. It is a specific pattern of localization - i.e., some combination of CN III, IV, V1, V2, or VI, along with evidence of optic neuropathy (CN II) - that indicates that there is pathology anterior to the cavernous sinus (because the opti...
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