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Would you consider restarting a SGLT2i at a reduced dose in a patient who you previously discontinued the medication because of an associated significant decline in eGFR?

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Would you consider restarting an SGLT2 inhibitor in a patient for whom you previously discontinued the medication due to a significant decline in eGFR?

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1 Answer
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Nephrology · University Hospitals Cleveland Medical Center
Answered on

Restarting an SGLT2i in a patient after a severe episode of AKI requires careful decision-making and patient agreement.

  1. If the AKI episode was deemed related to volume depletion (hemodynamically mediated AKI), I restart the SGLT2i at a lower dose. At the same time, I re-counsel the patent on fluid i...

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