How would you sequence medications in a young patient with history of VTE and severe atopic dermatitis after failure of dupilumab?

We can assume this is not exclusively Th2-driven based on the failure of dupilumab.

Consider patch testing prior to starting new treatment, using a short-course cyclosporine to clear skin if needed. Consider nbUVB phototherapy (home or office-delivered).

Consider off-label oral roflumilast (antiplat...