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Anti-CD38 Quadruplet Therapy in Multiple Myeloma: Meta-Analysis
Peer-reviewed clinical study
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Multiple Myeloma Clinical Practice Guidelines, 2026
For a patient with a lung abscess from aspiration, what duration of antibiotics should be used, and does the abscess need to be drained?
Mednet AITypical practice is ~4 weeks (often 4–6 weeks) of antibiotics if the patient is clinically improving, with longer courses individualized to clinical and imaging response. Most abscesses (>80%) resolve with antibiotics alone — drainage is generally reserved for cases that persist or worsen despite adequate therapy, or when an abscess is peripheral and not draining via the bronchial tree.
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Best approach for refractory RA after failing two TNF inhibitors?
Mednet AIAfter two TNF inhibitor failures, switching mechanism of action is preferred over cycling a third TNFi. EULAR recommends moving to a different bDMARD or tsDMARD. IL-6 receptor inhibitors and JAK inhibitors show the strongest evidence, with registry data favoring IL-6Ri effectiveness and JAK inhibitors showing higher remission rates at 26 weeks. Choice is guided by cardiovascular and malignancy risk assessment...
What about JAK inhibitor safety concerns?
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