Do the 8-year PACE-A results support a claim of equivalent long-term cancer control between SBRT and prostatectomy?
Or does reliance on BCF as the primary endpoint limit that conclusion?
This question is part of our ASTRO 2026 collaboration, inspired by the Plenary Session Presentation "Efficacy of Radical Prostatectomy Versus Stereotactic Body Radiotherapy (SBRT) for Localised Prostate Cancer: Results from an international Phase III Randomised Controlled Trial (PACE - A)" by Dr. Nicholas van As, MD, MB
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Cleveland Clinic
Answered on
The PACE-A trial is a phase 3 trial that randomized 123 patients with low- and intermediate-risk prostate cancer to a prostatectomy or prostate SBRT (36.25 Gy in 5 fractions) without androgen deprivation therapy (ADT). Overall, 94% had intermediate-risk disease and 84% of prostatectomies were roboti...
Join for free or sign in to see the full answer