Do you favor MRI-guided adaptive SBRT over conventional SBRT when baseline urinary symptoms raise concern for toxicity in a patient with localized prostate cancer?

Most trials of SBRT for prostate cancer had exclusion criteria based on baseline urinary symptoms. These vary somewhat from trial to trial, but if your patient is outside of the moderate range on the IPSS score, you may want to consider an alternative to SBRT. Also, the only randomized trial of whic...

While some patients with poor urinary quality of life might benefit from choosing other definitive management strategies (such as prostatectomy, which may improve upon their baseline symptoms, or fractionated XRT, which may have milder acute exacerbation per PACE-B and HYPO-RT-PC), proceeding with S...