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Do you expect a different response rate to neradomilast depending on the ILD phenotype?

For example, ground glass opacities on HRCT can correlate with cellular ILD, while honeycombing, reticulation, and traction bronchiectasis correlate with fibrotic ILD - do you think about these patient groups differently when it comes to your expectations for response to nerandomilast?
2 Answers
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Pulmonology · UMass Chan Medical School
Answered on

The best data to address this query come from the FIBRONEER-ILD trial, where approximately 70% of patients at enrollment had a UIP or UIP-like pattern on CT. The response to nerandomilast therapy was significant in both groups (with UIP or another pattern). In fact, the numerical results were greate...

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Rheumatology · The University of Chicago Medicine
Answered on

As a rheumatologist, I am particularly interested in the autoimmune ILD subtype and reviewed with great interest the subgroup analysis published in the Annals of Rheumatic Diseases by Anna-Maria Hoffman-Vold et al., PMID 42062162, which reports specifically on the 324 patients with autoimmune ILDs (...

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