How do you sequence IV steroids and IGF-1R blockade when inflammatory activity and proptosis coexist in a patient with active thyroid eye disease (TED)?
In light of the publication from Yen et al., PMID 42223386.
1 Answer
Mednet MemberInvited Expert
Ophthalmology · The Ohio State University Wexner Medical Center
Answered on
I don't find that steroids are actually necessary for patients who are receiving IGF1R inhibitors. The inflammation typically responds quite well to Teprotumumab (haven't tried Veligrotug yet), so steroids don't really add any benefit. These days, I only use IV steroids for patients who can't get IG...
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