What is your approach to the treatment of class IV lupus nephritis for a patient with AKI requiring dialysis?

To manage this patient's class IV lupus nephritis with dialysis-dependent AKI, I will initiate an aggressive induction regimen consisting of pulse IV methylprednisolone (500 to 1000 mg daily for 3 days) followed by an oral prednisone taper, combined with high-dose IV cyclophosphamide (NIH regimen) d...

If it is crescentic GN, I favor an aggressive immunosuppressive regimen (steroids and cyclophosphamide). I agree with Dr. @Dr. First Last. The biopsy findings are key.