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How do you decide whether or not to discontinue a critical medication likely contributing to severe peripheral eosinophilia without organ involvement?

Are there AEC thresholds where the medication is more likely to cause organ damage/DRESS?
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In a patient with new isolated severe eosinophilia (ie AEC >5k) without evidence of organ involvement, would you stop a potentially culprit anti-cancer medication?

9 physicians have voted

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