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Has the POTOMAC trial changed how you approach BCG maintenance schedule in high-risk NMIBC?

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Has the POTOMAC trial changed how you approach BCG maintenance schedule in high-risk NMIBC?

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2 Answers
Mednet Member
Mednet MemberInvited Expert
Urology · University of Washington School of Medicine
Answered on

The POTOMAC trial has not adjusted our planned maintenance schedules for BCG.

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Mednet Member
Mednet Member
Urology · Penn State Health
Answered on

Yes. If anything, these trials have reinforced for me how important it is to achieve adequate BCG maintenance in high-risk NMIBC. POTOMAC and CREST both used a two-year maintenance BCG backbone, with maintenance at months 3, 6, 12, 18, and 24, and both were positive trials. In POTOMAC specifically, ...

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