What treatment options do you consider after TNF failure in intestinal Behcet's with ongoing steroid dependence?

Colonic Behcet’s does not necessarily respond the way that IBD does. The evidence base for alternative therapies includes anti-interleukin-1, -6 and anti CD20. Anti Il-12/23 have also been used. Would discuss with a rheumatologist about which options are reasonable, depending on where else there are...

I like apremilast for joint manifestations; but for intestinal BD, I’d prefer tacrolimus.