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When do you opt for MRI brain in addition to CTA/CTP for evaluating eligibility for extended window thrombolysis?

Does the presence or absence of LVO make a difference? Does location of infarct matter?
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Would you require additional MRI for >4.5-hour thrombolysis elibility in cases without an LVO or MeVO?

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3 Answers
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Neurology · University of Virginia, School of Medicine
Answered on · Updated on

In a patient with disabling deficits (regardless of location), if the last known well time is unknown, but the symptom discovery was within 4.5 hours, we pursue an MRI to assess for IV thrombolysis eligibility after obtaining the initial CT head and CTA, and if there is no intervenable (per standard...

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Neurology · University of Calgary
Answered on

In my practice, never. It is too slow in our setup, where I practice. You can make the decision to treat or not treat on the basis of CT imaging alone. Similarly, if you are in a place where you have fast MR and use MR primarily, you will use MR to decide and will not, for example, do CT-based imagi...

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Neurology · Vanderbilt University Medical Center
Answered on

I would consider a good quality CTP, along with CTA and CT, to be adequate, with rare exceptions.

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