Would you ever consider a nonoperative approach for cutaneous angiosarcoma when a patient achieves a complete or near-complete clinical response after chemoradiotherapy?

Some limited surgery is generally favored, especially if the original site is still present after induction chemotherapy or chemo-RT. Extensive surgery and prolonged healing times are less favored, in particular if they will become barriers to prompt adjuvant RT delivery or systemic therapy delivery...

It is common for patients to achieve near-complete clinical response from induction paclitaxel alone. The robust near-complete clinical response rate from this study is unsurprising, based on the chemotherapy response expectation for this drug. Multiple studies show that patients who undergo surgery...