Among patients with anal SCC, is it reasonable to replace 5-FU with capecitabine when delivering definitive chemoradiotherapy with concurrent mitomycin C?
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1 Answers
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center
Yes, capecitabine can be substituted for infusional 5-FU in this setting. The NCCN guidelines include the capecitabine/mitomycin + RT regimen.