Are docetaxel and paclitaxel interchangeable for stage II-III HER2+ breast cancer patients receiving neoadjuvant chemotherapy with AC-THP?

Are there any studies that compare them?

1 Answer

Mednet MemberInvited Expert

Medical Oncology · University of Pittsburgh School of Medicine

Answered on

I believe docetaxel and paclitaxel are interchangeable in AC-THP for neoadjuvant chemotherapy for HER2 positive early-stage breast cancer. Decent phase II data from MSKCC confirm that the paclitaxel combination is well tolerated with PFS similar to CLEOPATRA.

(Dang et al., PMID 25547504).

The larger q...

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