I don't view UTIs as a contraindication to SGLT2i use, but I make a risk and benefit analysis with each patient. Bacterial UTI as well as mycotic vaginal infections may be a sign that the patient has excessive glycosuria from hyperglycemia. In general, treating hyperglycemia should lessen the freque...

UTIs should not be an absolute contraindication for SGLT2s. I’ll be particularly careful with female patients. Education of the patient as to what to expect and watch is most important. Risks vs benefits!

While I agree that it is not an absolute contraindication, we must thoroughly evaluate the patient to rule out any underlying urinary obstruction, stasis, severe BPH, or poorly controlled DM before we prescribe SGLT2i.