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Are there any clinical situations in which checking for anti-chromatin antibodies is helpful?

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Mednet Member
Mednet Member
Rheumatology · Georgetown University Hospital

Chromatin is the native complex of histones and DNA found in the cell nucleus of eukaryotes. The prevalence of anti-chromatin (nucleosome) antibodies in systemic lupus erythematosus (SLE) varies from 50% to 90%, being similar to that of the historic LE cell.

The question is whether this provides addi...

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