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Are there any concerns regarding side effects in changing from denosumab to zolendronic acid or vice versa?
Answer from: Medical Oncologist at Community Practice
In patients with advanced solid tumors and bone metastases, the anti-resorptive agents, zoledronic acid (ZA) or denosumab (D) are administered to prevent skeletal related events (SREs). The key toxicity of concern is medication-related osteonecrosis of the jaw (MRONJ). While patient and oral health ...
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