Are there any contraindications using nurtec in patients with headaches in the setting of recent RCVS?

I would be comfortable using Nurtec in a patient with a recent RCVS diagnosis. I am comfortable using triptans in patients with a prior stroke or MI with proper patient counseling unless they have critical/severe artery stenosis. I have had cluster headache patients who continue sumatriptan injections after a diagnosis of CAD or cerebral vascular disease.

So far, we have not seen increased cardiovascular events related to CGRP blockade in humans.

There was a study in mice by Mulder et al., PMID 32...