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Are there any data that suggest superiority of lenvatinib + pembrolizumab vs platinum-based cytotoxic chemotherapy for advanced or recurrent endometrial cancer?

Are there any planned trials to compare lenvatinib + pembrolizumab and platinum-based cytotoxic chemotherapy for advanced or recurrent endometrial cancer?
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In your experience, how has the efficacy of lenvatinib + pembrolizumab compared to the use of platinum based chemotherapy for recurrent endometrial cancer?

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1 Answer
Mednet Member
Mednet Member
Gynecologic Oncology · University of Texas Southwestern Medical Center
Answered on

A pertinent question that we should hopefully know the answer to relatively soon. KEYNOTE-775 did not address this question. However, the LEAP-001 trial, a phase 3 randomized, open-label, study is investigating and comparing the survival outcomes of Pembrolizumab and Lenvatinib vs chemotherapy (carb...

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