Are there any features that help differentiate Sjogren's-related CNS demyelinating plaques from multiple sclerosis in a patient with primary Sjogren's syndrome?
Answer from: at Academic Institution
This differentiation can be very difficult but the modified Barkhof's MRI criteria, perivenular lesions, and T2 lesions larger than 6 mm can be helpful in this regard. Helpful references:Kim et al., PMID 23736535Maggi et al., PMID 29328521
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