Are there any situations you would recommend prophylactic anticoagulation for a patient with Factor V heterozygosity?

Topics: Pediatric Oncology • Thrombosis • Hematology • Pediatric Hematology • Benign Hematology • Hemostasis/Thrombosis

FVL heterozygotes are often treated similarly to the general population. Aside from avoiding other VTE risk factors, are there situations where prophylaxis may be indicated where typically not done in the general population (low-risk surgery, obstetrics, strong family history but no personal history, etc.)?

Answer from: at Academic Institution

In short, no. Thrombotic risk is a complex variable with many contributing components. The presence of a single FVL allele, while it appears to increase the risk somewhat, is not sufficiently predictive of overall risk to provide a basis for administering prophylactic anticoagulation in a clinical s...

Comments

Medical Oncologist at Joliet Oncology Hematology Associates
Does this apply to pregnant patients with Factor V...

at University of Wisconsin
Yes

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