How would you manage symptomatic, bilateral subsegmental PE developed after long air travel?

I generally consider air travel to be a relatively weak provoking factor. Although the 2020 ASH guidelines do not address this, the ASH Guidelines from 2018 on management of VTE cite a 2.8-fold increased risk for VTE associated with air travel, which is roughly similar to the increased risk associat...

This is a very controversial topic, which is difficult to study and thus lacks significant evidence upon which to base firm recommendations. There is a systematic review that one could take a look at, which summarizes the current state of knowledge (Philbrick et al., PMID 17351849). Current ASH guid...

Current evidence/consensus suggests VTE after air travel should be approached as "unprovoked" VTE. Thus, typically suggest indefinite anticoagulation, ~6 months of full-dose DOAC followed by prophylactic dose. If bleeding risk or patient preference is to come off therapy, then suggest prophylaxis du...