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Are there certain disease domains in a patient with psoriatic arthritis that will make bimekizumab a particularly good option?

For example, in patients with many swollen/tender joints, enthesitis, nail involvement do you expect particularly good response? Are there patients in whom you will choose to use bimekizumab as the first-line biologic?
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Which disease domains or features make you more likely to recommend bimekizumab?

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2 Answers
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Mednet MemberInvited Expert
Rheumatology · OHSU
Answered on

Bimekizumab has shown comparable efficacy in PsA patients who are TNFi naive and TNFi inadequate responders. Therefore, I would choose bimekizumab in bDMARD-IR patients. My second answer might surprise you - I would choose bimekizumab in a PsA patient with recurrent uveitis.

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Mednet Member
Mednet MemberInvited Expert
Rheumatology · University of Rochester Medical Center
Answered on

Bimekizumab might be especially beneficial for patients with a heavy burden of arthritis and psoriasis.

First line therapy for any new PsA/PsO drug is always difficult in the US but we try.

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