Are there clinical, laboratory, or imaging features that can help distinguish primary Sjögren’s syndrome from secondary Sjögren’s in patients with overlapping inflammatory arthritis or positive rheumatoid factor?
For some clinicians it may be difficult to differentiate primary from secondary Sjogren's as 90% of Sjogren’s patients can have a positive rheumatoid factor. About 20-60% of Sjogren’s patients may also have inflammatory arthritis.
1 Answer
Mednet MemberInvited Expert
Rheumatology · University of California, Berkeley and San Francisco
Answered on
Such a good query. I don't really know, as associated SjD has been understudied. In my experience, associated Sjogren's does not look that different from Sjogren's alone. We have seen high ocular staining scores and markedly reduced unstimulated salivary flow in associated SjD (SLE, RA). In SjD, the...
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