Are there contraindications to giving radium-223 concurrently with palliative radiotherapy or systemic chemotherapy for mCRPC?
To what extent do you worry about overlapping myelosuppression? Is there any advantage to overlapping therapy?
Answer from: Medical Oncologist at Academic Institution
These combinations have not been approved, but studies of radium-223 with taxane therapy have been conducted in concert with docetaxel and have been presented in 2017 at GU ASCO by Michael Morris. These studies show that the combination is promising but myelosuppresive. The response rates to c...
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