Are there instances when you consider rituximab first line in a patient with class V LN?
Do you only reserve this for refractory cases?
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What best describes your use of rituximab in a patient with class V LN who has over 1gm proteinuria?
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2 Answers
Mednet MemberInvited Expert
Rheumatology · Uniformed Services University of the Health Sciences (USUHS)
Answered on
No, I would not. I agree with the KDIGO and ACR lupus nephritis guidelines, which state that rituximab should be reserved for refractory cases and cases where the patient is intolerant of therapies that have stronger efficacy evidence (e.g., calcineurin inhibitors, cyclophosphamide, and mycophenolat...
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Mednet MemberInvited Expert
Rheumatology · UT Southwestern Medical Center
Answered on
I do not use rituximab for first-line therapy for class V disease. I would consider it in refractory cases.
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