Are there instances when you recommend central line access when treating a patient using 3% sodium chloride for management of severe hyponatremia?  

At UCLA, our hospital policy allows for the administration of 3% sodium chloride via a peripheral intravenous catheter at infusion rates up to 50 mL/hr (PMID: 28471928, PMID: 27965228, PMID: 30745195).Moreover, a prospective, observational study demonstrated that patient and catheter phlebitis ra...