Are there instances when you use a 3% sodium chloride infusion for patients with chronic hyponatremia secondary to SIADH but who are asymptomatic or have only mild symptoms?  

One thing about 3% is that properly administered, the Na will rise. I have used it when I just want the PNa to increase ASAP, which for non neurological reasons may be something as simple as allowing the patient to go to the OR (they often have a minimal Na that they will give general anesthesia to)...

It has been argued that patients with chronic “asymptomatic” hyponatremia are not truly “asymptomatic.” It has been shown that these patients often have subtle cognitive impairment, gait instability, and are at increased risks for bone loss. Chronic hyponatremia has been show...